Polymorphisms at regions 1p22.1 (rs560426) and 8q24 (rs1530300) are risk markers for nonsyndromic cleft lip and/or palate in the Brazilian population.
نویسندگان
چکیده
Polymorphisms at Regions 1p22.1 (rs560426) and 8q24 (rs1530300) Are Risk Markers for Nonsyndromic Cleft Lip and/or Palate in the Brazilian Population Elizabete Bagordakis, L ıvia M aris Ribeiro Paranaiba, Luciano Abreu Brito, Sibele Nascimento de Aquino, Ana Camila Messetti, Herc ılio Martelli-Junior, Mario Sergio Oliveira Swerts, Edgard Graner, Maria Rita Passos-Bueno, and Ricardo D. Coletta* Department of Oral Diagnosis, School of Dentistry, State University of Campinas, Piracicaba, S~ao Paulo, Brazil Stomatology Clinic, Dental School, State University of Montes Claros, Montes Claros, Minas Gerais, Brazil Human Genome Research Center, Institute of Biosciences, University of S~ao Paulo, S~ao Paulo, Brazil Center for Rehabilitation of Craniofacial Anomalies, Dental School, University of Jos e Ros ario Vellano, Minas Gerais, Brazil
منابع مشابه
Polymorphisms at 1q32, 8q24, and 17q22 loci are associated with nonsyndromic cleft lip with or without cleft palate risk in the Slovak population.
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The aim of this study was to evaluate the association of the polymorphisms in TCN2 (rs1801198) gene and in MTRR (rs1801394) gene with nonsyndromic cleft lip and/or palate (NSCL/P) in a Brazilian population. Genomic DNA was extracted from buccal cells. The polymorphisms in TCN2 (rs1801198) and MTRR (rs1801394) genes were genotyped by carrying out real-time PCR and Taqman assay. Chi-square test w...
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BackgroundCleft lip and cleft palate (also, known as or facial clefts), are amongst the most common congenital deformities affecting the jaw and face as well as the most common defects associated with lip and palate. Thus, the current study was an attempt to investigate the prevalence and risk factors of or facial clefts in Iranian children.Materials and Methods:The present study, was conducted...
متن کاملParental cigarette smoking, transforming growth factor-alpha gene variant and the risk of orofacial cleft in Iranian infants
Objective(s):We investigated the influence of genetic variation of the transforming growth-factor alpha (TGFA) locus on the relationship between smoking and oral clefts. Materials and methods:In this study 105 Iranian infants with non-syndromic cleft lip/palate and 218 controls with non-cleft birth defects were examined to test for associations among maternal exposures, genetic markers, and ora...
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عنوان ژورنال:
- American journal of medical genetics. Part A
دوره 161A 5 شماره
صفحات -
تاریخ انتشار 2013